TRAINING PROGRAM
Description People Application Stipend

Selected publications for Susan E. Hodge, D.Sc.

  • Hodge SE. Conditioning on subsets of the data: Genetic applications with emphasis on ascertainment. Am J Hum Genet 43: 364–373, 1988.

  • Hodge SE, Greenberg, DA. Sensitivity of lod scores to changes in diagnostic status. Am J Hum Genet 50:1053–1066, 1992.

  • Hodge SE. Do bilineal pedigrees represent a problem for linkage analysis? Basic principles and simulation results for single-gene diseases with no heterogeneity. Genet Epidemiol 9: 191–206, 1992.

  • Hodge SE. Linkage analysis versus association analysis: Distinguishing between two models that explain disease-marker associations. Am J Hum Genet 53: 367–384, 1993.

  • Hodge SE, Elston RC.Lods, wrods, and mods: The interpretation of lod scores calculated under different models. Genet Epidemiol 11: 329–342, 1994.

  • Vieland VJ, Hodge SE. Inherent intractability of the ascertainment problem for pedigree data: A general likelihood framework. Am J Hum Genet 56: 33–43, 1995.

  • Hodge SE, Wickramaratne, P. Statistical pitfalls in detecting age-of-onset anticipation: The role of correlation in studying anticipation and detecting ascertainment bias. Psychiat Genet 5: 43–47, 1995.

  • Hodge SE. An oligogenic disease displaying weak marker associations: A summary of contributions to Problem 1 of GAW9. Genet Epidemiol 12: 545–554, 1995.

  • Durner M, Greenberg DA, Hodge SE. Phenocopies vs. genetic heterogeneity: Can we use phenocopy frequencies in linkage analysis to compensate for heterogeneity? Hum Hered 46: 265–273, 1996.

  • Hodge SE, Vieland VJ. The essence of single ascertainment. Genetics 144: 1215–1223, 1996.

  • Hodge SE, Abreu PC, Greenberg DA. Magnitude of type I error when single-locus linkage analysis is maximized over models: A simulation study. Am J Hum Genet 60: 217–227, 1997.

  • Hodge SE. Exact ELODs and exact power for affected sib pairs analyzed for linkage under simple right and wrong models. Am J Med Genet (Neuropsychiat Genet) 81: 66–72, 1998.

  • Hodge SE. A simple, unified approach to Bayesian risk calculations. J Genet Counseling 7: 235–261, 1998.

  • Leder RO, Mansbridge JN, Hallmayer J, Hodge SE. Familial psoriasis and HLA-B: Unambiguous support for linkage in 97 published families. Hum Hered 48: 198–211, 1998.

  • Hodge SE, Lebo RV, Yesley AR, Cheney SM, Angle H, Milunsky J. Calculating posterior cystic fibrosis risk with echogenic bowel and one characterized CF mutation. Am J Med Genet 82: 329–335, 1999.

  • Hodge SE, Boehnke M, Spence MA. Loss of information due to ambiguous haplotyping of SNPs. Nature Genet 21: 360–361, 1999.

  • Abreu PC, Greenberg DA, Hodge SE. Direct power comparisons between simple lod scores and NPL scores for linkage analysis in complex diseases. Am J Hum Genet 65: 847–857.

  • Hodge SE. "Model-free" vs. "model-based" linkage analysis: A false dichotomy? Am J Med Genet (Neuropsychiat Genet) 105:62–64, 2001.

  • Slager SL, Foroud T, Haghighi F, Spence MA, Hodge SE. Stoppage: An issue for segregation analysis. Genetic Epidemiology 20: 328–339, 2001.

  • Abreu PC, Hodge SE, Greenberg DA. Quantification of type I error probabilities for heterogeneity lod scores. Genet Epidemiol 22: 156–169, 2002.

  • Haghighi F, Hodge SE. Likelihood formulation of parent-of-origin effect on segregation analysis...Am J Hum Genet 70: 142–156, 2002.

  • Ahsan H, Hodge SE, Heiman GA, Begg MD, Susser ES. Relative risk for genetic associations: The case-parent triad as a variant of epidemiologic cohort designs. Int J Epidemiol 31: 669–678, 2002.

  • Spence MA, Greenberg DA, Hodge SE, VielandVJ. The emperor=s new clothes. Invited commentary, Am J Hum Genet, 72:1084–1087, 2003.

  • Flodman P, Hodge SE. Sex-specific mutation rates for X-linked disorders: Estimation and application. Hum Hered 55: 51–55, 2003.

  • Feenstra B, Greenberg DA, Hodge SE. Using lod scores to detect sex differences in male-female recombination fractions. Hum Hered 57: 100–108, 2004.

  • Lindholm E, Zhang J, Hodge SE, Greenberg DA. The reliability of haplotyping inference in nuclear families: Misassignment rates for SNPs and microsatellites. Hum Hered 57: 117–127, 2004.

  • Heiman GA, Hodge SE, Gorroochurn P, Zhang J, Greenberg DA. Effect of population stratification on false positive rates in association analysis. I. Elevation in false positive rates and comparison to confounding risk ratios (a simulation study). Hum Hered, 58: 30–39, 2004.

  • Gorroochurn P, Hodge SE, Heiman G, Greenberg DA. Effect of population stratification on case-control association studies. II. False-positive rates and their limiting behavior as the number of subpopulations increases. Hum Hered, 58: 40–48, 2004.

  • Lindholm E, Hodge SE,Greenberg DA Comparative informativeness for linkage of multiple SNPs and single microsatellites. Hum Hered, 58: 164–170, 2004.

  • Gorroochurn, P., Heiman, G.A., Hodge, S.E. & Greenberg, D.A. Centralizing the non-central chi-square: A new method to correct for population stratification in genetic case-control association studies. Genet Epidemiol 30: 277–289, 2006.

  • Gorroochurn, P. & Hodge, S.E. Estimating allele frequencies and inbreeding coefficients in K-allele models. Math Pop Studies 13: 83–103, 2006.

  • Fyer, A.J., Hamilton, S.P., Durner, M., Haghighi, F., Heiman, G.A., Costa, R., Evgrafov, O., Adams, P., de Leon, A.B., Tavaras, N., Klein, D.F., Hodge, S.E., Weissman, M.M. & Knowles, J.A. A third-pass genome scan in panic disorder: Evidence for multiple susceptibility loci. Biol Psychiatry 60: 388–401, 2006.

  • Strug, L.J & Hodge, S.E. An alternative foundation for the planning and evaluation of linkage analysis. I. Decoupling "error probabilities" from "measures of evidence." Hum Hered 61: 166–188, 2006.

  • Strug, L.J. & Hodge, S.E. An alternative foundation for the planning and evaluation of linkage analysis. II. Implications for multiple test adjustments. Hum Hered 61: 200–209, 2006.

  • Gorroochurn, P., Hodge, S.E., Heiman, G.A. & Greenberg, D.A. A unified approach for quantifying, testing and correcting population stratification in case-control association studies. Invited Article. Hum Hered 64: 149–159, 2007.

  • Hodge, S.E., Rodriguez-Murillo, L., Strug, L.J. & Greenberg, D.A. Multipoint lods provide reliable linkage evidence despite unknown limiting distribution: Type I error probabilities decrease with sample size for multipoint lods and mods. Genet Epidemiology, in press.