Jean Endicott, PhD

Research: Genetic studies of unipolar and bipolar affective disorders. Study of the course of illness in patients with various subtypes of affective and psychotic disorders. Treatment and follow-up studies of women with premenstrual dysphoric disorder as well as studies of other correlates of varying degrees of premenstrual change in mood and behavior.

Fellow Participation: Fellows can design and conduct their own studies in consultation with senior staff. Data sets are available for fellows to use to address issues other than those of primary focus in the funded studies. Fellows can also participate in the development of different ways of characterizing the course of illness in probands and family members and use the data to generate hypotheses for later testing with new data sets which are being collected. The major skills that would be developed are those related to diagnostic assessment, particularly of subjects who are not already identified as patients, assessment of course of illness and an awareness of issues involved in genetic and follow-up studies when multiple sources of information must be used.