The Department of Anesthesiology conducts a broad range of clinical and basic science research. Clinical research studies include patients in the operating rooms, neuroradiology suites and intensive care units. Laboratory studies range from whole animal physiology studies to subcelluar molecular studies. Faculty laboratories are located on the seventh floor of the Black Building, and the third floor of the Eye Institute. Studies involve patients, human volunteers, computer modeling, whole animals, isolated organs, tissues, and single cells. Techniques and facilities are available for animal surgery, physiological and electrophysiological recordings, drug analyses, cell culture, cell imaging, and biochemistry. In addition, a National Institute of Health Training Grant supports fellowship training.

The department has approximately 4,000 sq. ft. laboratory in the Black Building. This space was completely refurbished with a core molecular facility in November, 2000. It is equipped for in vivo hemodynamic and respiratory measurements as well as necessary equipment for cell biology, electrophysiology, biochemical, and molecular biology analyses and is adjacent to a library and conference room shared with the Department of Pharmacology.

There is also 4,000 sq. ft of research space on the third floor of the Eye Institute that was completely renovated in 2003. In July 2003 the neurobiology anesthesia group moved to these new laboratories. Facilities include electrophysiology stations for two-electrode voltage clamp, whole cell patch clamp, single channel recording with ultra-rapid perfusion, and slice patch recordings. A well isolated quiet room for rodent behavioral experiments, a full set up for in vivo microdialysis work and 3 HPLCs with electrochemical detectors, a microscopy station for intracellular Ca⁺⁺ studies, and a chemiluminescence imaging station are present. Amply bench space is available for cell biological and molecular biological work. Externally vented hood for work with volatile agents and radioactivity, a dedicated radioactivity room, cold room, and a utility room with an automated dish washer and an autoclave, and a cell culture clean room are shared by all investigators. In addition, the core equipment area houses preparative centrifuge, ultracentrifuge, desk top refrigerated centrifuge, -80°C freezers, gradient thermal cyclers, fluorescent microplate reader, and an ice machine. The research area has a dedicated office space for an administrative assistant adjacent to a conference room equipped with an LCD projector.